Real-world safety of aliskiren in primary hypertension: A cross-database study

Meirong Shan; Qian Guo; Ruofei Li; Ni Li; Yanhua Fu; Huanyu Qi; Ge Zhang; Qian Wang; Xingli Xu; Jinchuan Lai

doi:10.1371/journal.pone.0346326

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Open Access

Peer-reviewed

Research Article

Real-world safety of aliskiren in primary hypertension: A cross-database study

Meirong Shan,

Roles Conceptualization, Writing – original draft

Affiliation Department of Geriatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China

https://orcid.org/0000-0002-8213-1236

⨯
Qian Guo,

Roles Data curation, Methodology

Affiliation Department of Rhinology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
⨯
Ruofei Li,

Roles Data curation, Supervision

Affiliation Institute of Cardiovascular Diseases & Department of Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
⨯
Ni Li,

Roles Data curation, Supervision

Affiliation Department of Obstetrics and Gynecology, First People’s Hospital of Foshan, Foshan, Guangdong, China
⨯
Yanhua Fu,

Roles Data curation, Supervision

Affiliation Department of Hepatology, Qilu Hospital of Shandong University (Qingdao), Qingdao, Shandong, China
⨯
Huanyu Qi,

Roles Writing – review & editing

Affiliation Department of Gastrointestinal Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
⨯
Ge Zhang,

Roles Writing – review & editing

Affiliations Department of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China, Key Laboratory of Cardiac Injury and Repair of Henan Province; Henan Province Clinical Research Center for Cardiovascular Diseases, Zhengzhou, Henan, China
⨯
Qian Wang ,

Roles Funding acquisition, Writing – review & editing

* E-mail: qiansmile320@163.com (QW); xuxingli623@163.com (XX); 15881157200@163.com (JL)

Affiliation Department of Geriatrics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
⨯
Xingli Xu ,

Roles Funding acquisition, Writing – review & editing

* E-mail: qiansmile320@163.com (QW); xuxingli623@163.com (XX); 15881157200@163.com (JL)

Affiliation Institute of Cardiovascular Diseases & Department of Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
⨯
Jinchuan Lai

Roles Funding acquisition, Writing – review & editing

* E-mail: qiansmile320@163.com (QW); xuxingli623@163.com (XX); 15881157200@163.com (JL)

Affiliation Institute of Cardiovascular Diseases & Department of Cardiology, Sichuan Provincial People’s Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, China
⨯

Real-world safety of aliskiren in primary hypertension: A cross-database study

Meirong Shan,
Qian Guo,
Ruofei Li,
Ni Li,
Yanhua Fu,
Huanyu Qi,
Ge Zhang,
Qian Wang,
Xingli Xu,
Jinchuan Lai

Published: April 3, 2026
https://doi.org/10.1371/journal.pone.0346326

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