Integrating systemic inflammation biomarker and clinical predictors for surgical site infection risk assessment in closed pilon fractures: A risk prediction model

Lin Jin; Yanci Zhang; Jiale Li; Lianxin Song; Yang Luo; Tianhua Dong; Xuebin Zhang

doi:10.1371/journal.pone.0346298

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Open Access

Peer-reviewed

Research Article

Integrating systemic inflammation biomarker and clinical predictors for surgical site infection risk assessment in closed pilon fractures: A risk prediction model

Lin Jin ,

Roles Data curation, Writing – original draft, Writing – review & editing

¶☯ Lin Jin, Yanci Zhang and Jiale Li contributed equally to this work.

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Yanci Zhang ,

Roles Data curation, Investigation, Validation, Writing – original draft, Writing – review & editing

¶☯ Lin Jin, Yanci Zhang and Jiale Li contributed equally to this work.

Affiliation Trauma Center, Hebei Medical University First Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Jiale Li ,

Roles Data curation, Software, Validation, Visualization

¶☯ Lin Jin, Yanci Zhang and Jiale Li contributed equally to this work.

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Lianxin Song,

Roles Data curation, Formal analysis, Investigation, Project administration

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Yang Luo,

Roles Data curation, Supervision

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Tianhua Dong,

Roles Data curation

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China
⨯
Xuebin Zhang

Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision

* E-mail: xuebin_1982@126.com

Affiliation Department of Orthopaedic Surgery, Hebei Medical University Third Hospital, Shijiazhuang, Hebei, People’s Republic of China

https://orcid.org/0000-0002-2595-6696

⨯

Integrating systemic inflammation biomarker and clinical predictors for surgical site infection risk assessment in closed pilon fractures: A risk prediction model

Lin Jin,
Yanci Zhang,
Jiale Li,
Lianxin Song,
Yang Luo,
Tianhua Dong,
Xuebin Zhang

Published: April 6, 2026
https://doi.org/10.1371/journal.pone.0346298

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Surgical and invasive medical procedures
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Inflammation
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Biomarkers
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Medical risk factors
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Orthopedic surgery
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Traumatic injury risk factors
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