A U-Net model for epidermal segmentation in optical coherence tomography images of actinic keratosis

Theofanis Angelis; Peter A. Philipsen; Vinzent K. Ortner; Gabriella Fredman; Merete Haedersdal; Gavrielle R. Untracht

doi:10.1371/journal.pone.0346059

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Open Access

Peer-reviewed

Research Article

A U-Net model for epidermal segmentation in optical coherence tomography images of actinic keratosis

Theofanis Angelis ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: tangelis@outlook.com

Affiliations Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

https://orcid.org/0009-0001-4215-6818

⨯
Peter A. Philipsen,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark

https://orcid.org/0000-0002-9656-733X

⨯
Vinzent K. Ortner,

Roles Conceptualization, Validation, Writing – review & editing

Affiliation Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark
⨯
Gabriella Fredman,

Roles Data curation, Validation, Writing – review & editing

Affiliation Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark
⨯
Merete Haedersdal,

Roles Funding acquisition, Supervision, Writing – review & editing

Affiliations Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, Department of Clinical Medicine, Faculty of Health and Medical Science, University of Copenhagen, Copenhagen, Denmark
⨯
Gavrielle R. Untracht

Roles Conceptualization, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

Affiliations Department of Dermatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, Department of Health Technology, Technical University of Denmark, Kongens Lyngby, Denmark

https://orcid.org/0000-0001-6334-0625

⨯

A U-Net model for epidermal segmentation in optical coherence tomography images of actinic keratosis

Theofanis Angelis,
Peter A. Philipsen,
Vinzent K. Ortner,
Gabriella Fredman,
Merete Haedersdal,
Gavrielle R. Untracht

Published: June 5, 2026
https://doi.org/10.1371/journal.pone.0346059

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Lesions
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Tomography
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Actinic keratosis
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