PRognostic and predictive potential Of multiparametric dynamic whole-body 18F-FDG PET Imaging using a Long axial field-of-view (LAFOV) system for FIRST-line chemo-immunotherapy efficacy in advanced non-small cell lung cancer: PROFIL-1 study protocol

• Margaux Geier ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: margaux.geier@chu-brest.fr

  Affiliations Univ Brest, Inserm, UMR 1304, GETBO, Brest, France, Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  https://orcid.org/0000-0002-4884-5825

  ⨯
• Karim Amrane,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, CH Morlaix, Morlaix, France

  ⨯
• David Bourhis,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Univ Brest, Inserm, UMR 1304, GETBO, Brest, France, Department of Molecular Imaging and Theranostics, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Pierre-Yves Le Roux,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliations Univ Brest, Inserm, UMR 1304, GETBO, Brest, France, Department of Molecular Imaging and Theranostics, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Jessica Nguyen,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

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• Estelle Dhamelincourt,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Renaud Descourt,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Gilles Quéré,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Marie Guegan,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Medical Oncology, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Benjamin Besse,

  Roles Writing – review & editing

  Affiliations Department of Medical Oncology, International Center for Thoracic Cancers (CICT), Gustave Roussy, Villejuif, France, Paris-Saclay University, Paris, France

  ⨯
• Désirée Déandreis,

  Roles Writing – review & editing

  Affiliations Paris-Saclay University, Paris, France, Imaging Department, Nuclear Medicine Service, Gustave Roussy, Villejuif, France

  ⨯
• Florent Besson,

  Roles Writing – review & editing

  Affiliation Department of Nuclear Medicine and Molecular Imaging, Paris-Saclay University, AP-HP, CHU Bicêtre, DMU SMART IMAGING, Le Kremlin-Bicêtre, Paris, France

  ⨯
• Sylvain Faure,

  Roles Writing – review & editing

  Affiliation Laboratoire de Mathématique d’Orsay, CNRS, Université Paris-Saclay, Orsay City, France

  https://orcid.org/0000-0002-4069-0523

  ⨯
• Nicolas Karakatsanis,

  Roles Writing – review & editing

  Affiliation Department of Radiology, Weill Cornell Medical College, New York, New York, United States of America

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• Pierre-Yves Salaun,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliations Univ Brest, Inserm, UMR 1304, GETBO, Brest, France, Department of Molecular Imaging and Theranostics, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Mathieu Pavoine,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Imaging and Theranostics, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  ⨯
• Vincent Bourbonne,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliations Radiation Oncology Department, University Hospital, Brest, France, LaTIM, INSERM, UMR 1101, University of Brest, ISBAM, UBO, UBL, Brest, France

  ⨯
• François Lucia,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – review & editing

  Affiliations Radiation Oncology Department, University Hospital, Brest, France, LaTIM, INSERM, UMR 1101, University of Brest, ISBAM, UBO, UBL, Brest, France

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•  [ ... ],
• Ronan Abgral

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Univ Brest, Inserm, UMR 1304, GETBO, Brest, France, Department of Molecular Imaging and Theranostics, Cancer & Imaging Institute, CHU La Cavale Blanche, University Hospital of Brest, Brest, France

  https://orcid.org/0000-0002-5585-2564

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