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Open Access
Peer-reviewed
Research Article
Annotation-free prediction of immunotherapy response in melanoma using single-cell transcriptomic data
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Da Eun Oh ,
Contributed equally to this work with: Da Eun Oh, Gaeun Kee, Ji-Hye Oh
Roles Data curation, Formal analysis, Investigation, Resources, Visualization, Writing – original draft
Affiliations Bioinformatics Core Laboratory, Convergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea, Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Gaeun Kee ,
Contributed equally to this work with: Da Eun Oh, Gaeun Kee, Ji-Hye Oh
Roles Formal analysis, Investigation, Visualization, Writing – original draft
Affiliations Department of Medical Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Department of Information Medicine, Asan Medical Center, Seoul, Republic of Korea
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Ji-Hye Oh ,
Contributed equally to this work with: Da Eun Oh, Gaeun Kee, Ji-Hye Oh
Roles Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Visualization, Writing – original draft
Affiliation Bioinformatics Core Laboratory, Convergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea
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Wonkyung Kim,
Roles Data curation, Investigation, Writing – original draft
Affiliations Department of Medical Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Young Gwang Kang,
Roles Data curation, Resources
Affiliations Department of Medical Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Chae Won Park,
Roles Data curation, Methodology
Affiliations Department of Medical Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Tae Joon Jun ,
Roles Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Visualization
* E-mail: taejoon@chilab.kr (TJJ); co.sung@amc.seoul.kr (COS)
Affiliation Department of Medical Informatics and Statistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Chang Ohk Sung
Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Visualization, Writing – original draft
* E-mail: taejoon@chilab.kr (TJJ); co.sung@amc.seoul.kr (COS)
Affiliations Bioinformatics Core Laboratory, Convergence Medicine Research Center, Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea, Department of Medical Science, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea, Department of Pathology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
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Annotation-free prediction of immunotherapy response in melanoma using single-cell transcriptomic data
- Da Eun Oh,
- Gaeun Kee,
- Ji-Hye Oh,
- Wonkyung Kim,
- Young Gwang Kang,
- Chae Won Park,
- Tae Joon Jun,
- Chang Ohk Sung
- Published: February 27, 2026
- https://doi.org/10.1371/journal.pone.0343633