Exploring the effects of IFN-τ on LPS-induced endometritis in cows based on transcriptomics

Pan Liu; Yaofeng Zhang; Xu Chen; Lijun Tang; Wenxiu Xu; Guigui Wang; Duoqi Zhang; Junfeng Liu

doi:10.1371/journal.pone.0343553

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Open Access

Peer-reviewed

Research Article

Exploring the effects of IFN-τ on LPS-induced endometritis in cows based on transcriptomics

Pan Liu,

Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China

https://orcid.org/0009-0002-5619-0846

⨯
Yaofeng Zhang,

Roles Conceptualization, Data curation, Writing – original draft

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯
Xu Chen,

Roles Conceptualization, Data curation

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯
Lijun Tang,

Roles Conceptualization, Data curation

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China, Sichuan Vocational and Technical College, Suining, Sichuan, People's Republic of China
⨯
Wenxiu Xu,

Roles Investigation, Methodology

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯
Guigui Wang,

Roles Investigation, Methodology

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯
Duoqi Zhang,

Roles Investigation, Validation

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯
Junfeng Liu

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: ljfdky@126.com

Affiliations College of Animal Science and Technology, Tarim University, Alar, Xinjiang, People's Republic of China, Tarim Animal Disease Diagnosis and Prevention and Control Engineering Laboratory, Xinjiang Production and Construction Corps, Aral, Xinjiang, People's Republic of China
⨯

Exploring the effects of IFN-τ on LPS-induced endometritis in cows based on transcriptomics

Pan Liu,
Yaofeng Zhang,
Xu Chen,
Lijun Tang,
Wenxiu Xu,
Guigui Wang,
Duoqi Zhang,
Junfeng Liu

Published: March 5, 2026
https://doi.org/10.1371/journal.pone.0343553

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Gene expression
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Immune receptor signaling
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Viral gene expression
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Cytokine receptors
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RNA sequencing
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MAPK signaling cascades
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Transcription factors
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Transcriptome analysis
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