Targeted near-infrared imaging utilizing a cathepsin-activated fluorophore for the intraoperative detection of canine insulinoma

• Maureen A. Griffin ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Maureen.Griffin@colostate.edu

  Current address: Department of Clinical Sciences, Colorado State University College of Veterinary Medicine and Biomedical Sciences, Fort Collins, Colorado, United States

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0001-9714-1579

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• Enrico Radaelli,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pathobiology, Penn Vet Comparative Pathology Core, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Charles-Antoine Assenmacher,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliation Department of Pathobiology, Penn Vet Comparative Pathology Core, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0003-0073-2730

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• Sunil Singhal,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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• Robert E. Roses,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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• Brian K. Flesner,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Darko Stefanovski,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

  https://orcid.org/0000-0002-4654-0569

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• Nimar Gill,

  Roles Data curation, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Jennifer L. Huck,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Heather Scavello,

  Roles Data curation, Project administration, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Jillian Verrelle,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Pathobiology, Penn Vet Comparative Pathology Core, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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• Kristen Farrell,

  Roles Methodology, Validation, Writing – review & editing

  Affiliation Cancer Biology and Experimental Therapeutics Laboratory, Colorado State University College of Veterinary Medicine and Biomedical Sciences, Fort Collins, Colorado, United States of America

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• David E. Holt

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Clinical Sciences and Advanced Medicine, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, United States of America

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