Multidimensional analysis of screening results of deafness susceptibility genes in 3066 newborns of different altitudes and nationalities in Xining, Qinghai(ISRCTN89197487)

Benhong Ren; Yazhen Wu; Wenyuan Gan; Qingping Zhang; Dandan Yang; Wenjun Cao; Xiaoli Zhang; Yuan Jiang; Ying Zhang; Bin Guo; Yongxia Tie; Jiannan Liu; Guilan Cai; Yi Wang; Yanyan Ma

doi:10.1371/journal.pone.0342920

Loading metrics

Open Access

Peer-reviewed

Research Article

Multidimensional analysis of screening results of deafness susceptibility genes in 3066 newborns of different altitudes and nationalities in Xining, Qinghai(ISRCTN89197487)

Benhong Ren,

Roles Data curation, Formal analysis, Investigation, Software, Validation, Visualization, Writing – original draft

Affiliations Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China, Otolaryngology Major, Clinical Medical College, Qinghai University, Xining City, Qinghai Province, China, Department of Otolaryngology-Head and Neck Surgery, Shanxi Fenyang Hospital, Fenyang City, Lvliang City, Shanxi Province, China
⨯
Yazhen Wu,

Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision

Affiliation Department of Neonatal Intensive Care Medicine, Affiliated Hospital of Qinghai University, Xining, Qinghai Province, China
⨯
Wenyuan Gan,

Roles Data curation, Investigation

Affiliations Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China, Otolaryngology Major, Clinical Medical College, Qinghai University, Xining City, Qinghai Province, China
⨯
Qingping Zhang,

Roles Data curation, Formal analysis, Investigation

Affiliations Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China, Otolaryngology Major, Clinical Medical College, Qinghai University, Xining City, Qinghai Province, China
⨯
Dandan Yang,

Roles Investigation, Methodology, Project administration, Resources

Affiliation Department of Neonatal Intensive Care Medicine, Affiliated Hospital of Qinghai University, Xining, Qinghai Province, China
⨯
Wenjun Cao,

Roles Investigation, Resources

Affiliation Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China
⨯
Xiaoli Zhang,

Roles Investigation, Resources

Affiliation Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China
⨯
Yuan Jiang,

Roles Methodology, Supervision, Validation

Affiliation Central Laboratory, Affiliated Hospital of Qinghai University, Xining City, Qinghai Province, China
⨯
Ying Zhang,

Roles Investigation, Resources

Affiliation Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China
⨯
Bin Guo,

Roles Investigation, Resources

Affiliation Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China
⨯
Yongxia Tie,

Roles Investigation, Resources

Affiliation People’s Hospital of Minhe Hui and Tu Autonomous County, Haidong City, Qinghai Province, China
⨯
Jiannan Liu,

Roles Investigation, Resources

Affiliation Qinghai Maternal and Child Health-Care Hospital, Xining City, Qinghai Province, China
⨯
Guilan Cai,

Roles Investigation, Resources

Affiliation People’s Hospital of Datong County, Datong, Qinghai Province, China
⨯
Yi Wang ,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing, Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: wegreatgroup@163.com (YW); mayanyan_research@qhu.edu.cn (YM)

Affiliations Otolaryngology Department, Qinghai University Affiliated Hospital, Xining, Qinghai Province, China, Department of Otolaryngology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

https://orcid.org/0009-0001-5320-1063

⨯
Yanyan Ma

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources

* E-mail: wegreatgroup@163.com (YW); mayanyan_research@qhu.edu.cn (YM)

Affiliation Department of Pediatrics, Affiliated Hospital of Qinghai University, Xining, Qinghai Province, China
⨯

Multidimensional analysis of screening results of deafness susceptibility genes in 3066 newborns of different altitudes and nationalities in Xining, Qinghai(ISRCTN89197487)

Benhong Ren,
Yazhen Wu,
Wenyuan Gan,
Qingping Zhang,
Dandan Yang,
Wenjun Cao,
Xiaoli Zhang,
Yuan Jiang,
Ying Zhang,
Bin Guo

Published: February 24, 2026
https://doi.org/10.1371/journal.pone.0342920

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Mutation detection
Is the Subject Area "Mutation detection" applicable to this article?

Thanks for your feedback.
Deafness
Is the Subject Area "Deafness" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.
Tibetan people
Is the Subject Area "Tibetan people" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Genetic screens
Is the Subject Area "Genetic screens" applicable to this article?

Thanks for your feedback.
Neonates
Is the Subject Area "Neonates" applicable to this article?

Thanks for your feedback.
Mutation
Is the Subject Area "Mutation" applicable to this article?

Thanks for your feedback.