AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer

Yuhei Miyasaka; Hanae Yoshida; Naoko Okano; Hirofumi Shimada; Nobuteru Kubo; Hidemasa Kawamura; Tatsuya Ohno

doi:10.1371/journal.pone.0342481

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Open Access

Peer-reviewed

Research Article

AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer

Yuhei Miyasaka,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliations Gunma University Heavy Ion Medical Center, Maebashi, Japan, Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan

https://orcid.org/0000-0001-5137-1862

⨯
Hanae Yoshida,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliations Gunma University Advanced Particle Beam Medical Science Joint Research Course (Hitachi, Ltd.), Maebashi, Japan, Healthcare Innovation Center, Hitachi, Ltd., Tokyo, Japan
⨯
Naoko Okano ,

Roles Conceptualization, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: okano.n@gunma-u.ac.jp

Affiliations Gunma University Heavy Ion Medical Center, Maebashi, Japan, Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan, Gunma University Advanced Particle Beam Medical Science Joint Research Course (Hitachi, Ltd.), Maebashi, Japan

https://orcid.org/0000-0001-7669-6110

⨯
Hirofumi Shimada,

Roles Data curation, Resources

Affiliation Gunma University Heavy Ion Medical Center, Maebashi, Japan
⨯
Nobuteru Kubo,

Roles Resources, Writing – review & editing

Affiliations Gunma University Heavy Ion Medical Center, Maebashi, Japan, Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan
⨯
Hidemasa Kawamura,

Roles Resources, Writing – review & editing

Affiliations Gunma University Heavy Ion Medical Center, Maebashi, Japan, Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan

https://orcid.org/0000-0003-4899-1715

⨯
Tatsuya Ohno

Roles Funding acquisition, Project administration, Supervision

Affiliations Gunma University Heavy Ion Medical Center, Maebashi, Japan, Department of Radiation Oncology, Gunma University Graduate School of Medicine, Maebashi, Japan
⨯

AI-based prediction of recurrence after carbon ion radiotherapy for early stage non-small cell lung cancer

Yuhei Miyasaka,
Hanae Yoshida,
Naoko Okano,
Hirofumi Shimada,
Nobuteru Kubo,
Hidemasa Kawamura,
Tatsuya Ohno

Published: February 10, 2026
https://doi.org/10.1371/journal.pone.0342481

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