Separation-like irregularity and sample size optimism in high-discrimination logistic prediction models

• Ye Liang ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶☯ These authors contributed equally to this work as co-first authors.

  Affiliation Department of Industrial and Systems Engineering, University of Iowa, Iowa City, Iowa, United States of America

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• Louis Shuo Wang ,

  Roles Formal analysis, Investigation, Validation, Writing – original draft

  * E-mail: swang116@vols.utk.edu

  ¶☯ These authors contributed equally to this work as co-first authors.

  Affiliation Department of Mathematics, University of Tennessee, Knoxville, Tennessee, United States of America

  https://orcid.org/0009-0007-0977-7894

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• Jiguang Yu ,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – original draft

  ¶☯ These authors contributed equally to this work as co-first authors.

  Affiliation College of Engineering, Boston University, Boston, Massachusetts, United States of America

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• Xin Zan

  Roles Project administration, Supervision, Writing – review & editing

  Affiliation Department of Industrial and Systems Engineering, University of Iowa, Iowa City, Iowa, United States of America

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