Medication adherence trajectories and association with risk factors and clinical outcomes in type 2 diabetes treatment

Sara Mucherino; Valentina Orlando; Marcia Vervloet; Yvette Weesie; Liset van Dijk; Enrica Menditto

doi:10.1371/journal.pone.0342056

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Open Access

Peer-reviewed

Research Article

Medication adherence trajectories and association with risk factors and clinical outcomes in type 2 diabetes treatment

Sara Mucherino ,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

* E-mail: sara.mucherino@unina.it

Affiliations Department of Pharmacy, University of Naples Federico II, Naples, Italy, Center of Drug Utilization and Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy

https://orcid.org/0000-0003-3357-5655

⨯
Valentina Orlando,

Roles Funding acquisition, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Department of Pharmacy, University of Naples Federico II, Naples, Italy, Center of Drug Utilization and Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy
⨯
Marcia Vervloet,

Roles Formal analysis, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Netherlands Institute for Health Services Research (Nivel), Utrecht, The Netherlands
⨯
Yvette Weesie,

Roles Data curation, Formal analysis, Investigation, Methodology

Affiliation Netherlands Institute for Health Services Research (Nivel), Utrecht, The Netherlands
⨯
Liset van Dijk,

Roles Conceptualization, Investigation, Supervision, Validation, Writing – review & editing

Affiliations Netherlands Institute for Health Services Research (Nivel), Utrecht, The Netherlands, Department of PharmacoTherapy, Epidemiology & Economics (PTEE), Faculty of Science and Engineering, Groningen Research, Institute of Pharmacy, University of Groningen, Groningen, The Netherlands
⨯
Enrica Menditto

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – review & editing

Affiliations Department of Pharmacy, University of Naples Federico II, Naples, Italy, Center of Drug Utilization and Pharmacoeconomics (CIRFF), University of Naples Federico II, Naples, Italy
⨯

Medication adherence trajectories and association with risk factors and clinical outcomes in type 2 diabetes treatment

Sara Mucherino,
Valentina Orlando,
Marcia Vervloet,
Yvette Weesie,
Liset van Dijk,
Enrica Menditto

Published: February 20, 2026
https://doi.org/10.1371/journal.pone.0342056

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