Identifying biomarkers for diagnosis and disease activity monitoring in PSC-IBD and UC through proteomic profiling: A prospective, biomarker discovery single-center study protocol

• Ondrej Fabian ,

  Roles Conceptualization, Funding acquisition, Methodology, Supervision, Writing – original draft

  * E-mail: ondrej.fabian@ikem.cz

  Affiliations Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Department of Pathology and Molecular Medicine, Faculty of Medicine, Charles University and Thomayer Hospital, Prague, Czech Republic

  https://orcid.org/0000-0002-0393-2415

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• Lukas Bajer,

  Roles Data curation, Investigation, Methodology

  Affiliations Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Department of Internal Medicine, Motol University Hospital and Second Faculty of Medicine, Charles University, Prague, Czech Republic

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• Peter Macinga,

  Roles Data curation, Investigation

  Affiliation Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Jan Brezina,

  Roles Data curation, Investigation

  Affiliation Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Mojmir Hlavaty,

  Roles Data curation, Investigation

  Affiliation Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Pavel Drastich,

  Roles Data curation, Investigation

  Affiliation Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Pavel Wohl,

  Roles Data curation, Investigation

  Affiliation Department of Gastroenterology and Hepatology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Karel Harant,

  Roles Data curation, Methodology, Software, Writing – original draft

  Affiliation Proteomics Core Facility, Faculty of Science, Charles University, Vestec, Czech Republic

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• Pavel Talacko,

  Roles Data curation, Investigation, Methodology, Software

  Affiliation Proteomics Core Facility, Faculty of Science, Charles University, Vestec, Czech Republic

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• Eva Sticova,

  Roles Data curation, Investigation

  Affiliations Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Department of Pathology, Royal Vinohrady University Hospital, Srobarova, Prague, Czech Republic

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• Andrea Vajsova,

  Roles Data curation, Investigation

  Affiliations Clinical and Transplant Pathology Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, Institute of Pathology of the First Faculty of Medicine and General Teaching Hospital, Studnickova, Prague, Czech Republic

  https://orcid.org/0000-0002-8473-8664

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• Alena Bohdanecka,

  Roles Investigation, Methodology, Software

  Affiliation Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

  https://orcid.org/0009-0006-0573-6684

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• Filip Tichanek,

  Roles Conceptualization, Formal analysis, Methodology, Software

  Affiliation Department of Informatics, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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• Monika Cahova

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft

  Affiliation Experimental Medicine Centre, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

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