Multi-omics analysis reveals STING activation mediates NLRP3-related pyroptosis and exacerbates myocardial ischemia-reperfusion injury

• Xuehu Zhang ,

  Contributed equally to this work with: Xuehu Zhang, Aoqin Gu

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

  https://orcid.org/0009-0009-5583-4110

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• Aoqin Gu ,

  Contributed equally to this work with: Xuehu Zhang, Aoqin Gu

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Ningxia Medical University, Yinchuan, Ningxia, China

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• Lirong Zhou,

  Roles Investigation, Writing – original draft, Writing – review & editing

  Affiliation Ningxia Medical University, Yinchuan, Ningxia, China

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• Yuru Ma,

  Roles Methodology, Writing – original draft, Writing – review & editing

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

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• Peng Wu,

  Roles Resources, Writing – original draft, Writing – review & editing

  Affiliation Ningxia Medical University, Yinchuan, Ningxia, China

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• Baozhen Zhu,

  Roles Software, Writing – original draft, Writing – review & editing

  Affiliation Ningxia Medical University, Yinchuan, Ningxia, China

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• Ru Yan,

  Roles Validation, Writing – original draft, Writing – review & editing

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

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• Guangzhi Cong ,

  Roles Methodology, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: schatz1898@gmail.com (GC), maxueping4033@126.com (XM) jsbxn@163.com (SJ)

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

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• Xueping Ma ,

  Roles Project administration, Validation, Writing – original draft, Writing – review & editing

  * E-mail: schatz1898@gmail.com (GC), maxueping4033@126.com (XM) jsbxn@163.com (SJ)

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

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• Shaobin Jia

  Roles Funding acquisition, Project administration, Writing – original draft, Writing – review & editing

  * E-mail: schatz1898@gmail.com (GC), maxueping4033@126.com (XM) jsbxn@163.com (SJ)

  Affiliation Heart Center & Department of Cardiovascular Diseases, General Hospital of Ningxia Medical University, Yinchuan, Ningxia, China

  https://orcid.org/0000-0002-8545-1067

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