Risk of prostatitis in patients with type 2 diabetes mellitus: An observational retrospective cohort study of canagliflozin versus other antihyperglycemic agents using propensity score matching

Zhong Yuan; Carolyn H. Jeffcoat; Saberi Rana Ali; Anthony G. Sena; Martijn J. Schuemie; Patrick B. Ryan; Sergio A. Fonseca

doi:10.1371/journal.pone.0341745

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Open Access

Peer-reviewed

Research Article

Risk of prostatitis in patients with type 2 diabetes mellitus: An observational retrospective cohort study of canagliflozin versus other antihyperglycemic agents using propensity score matching

Zhong Yuan ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: zyuan6@its.jnj.com

Affiliation Johnson & Johnson, Horsham, Pennsylvania, United States of America

https://orcid.org/0000-0002-5824-2040

⨯
Carolyn H. Jeffcoat,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Johnson & Johnson, Horsham, Pennsylvania, United States of America
⨯
Saberi Rana Ali,

Roles Conceptualization, Investigation, Writing – original draft

Affiliation Johnson & Johnson, Titusville, New Jersey, United States of America

https://orcid.org/0009-0009-1581-8431

⨯
Anthony G. Sena,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Johnson & Johnson, Titusville, New Jersey, United States of America

https://orcid.org/0000-0001-8630-5347

⨯
Martijn J. Schuemie,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Johnson & Johnson, Titusville, New Jersey, United States of America
⨯
Patrick B. Ryan,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation Johnson & Johnson, Titusville, New Jersey, United States of America
⨯
Sergio A. Fonseca

Roles Conceptualization, Investigation, Writing – review & editing

Affiliation Johnson & Johnson, Titusville, New Jersey, United States of America
⨯

Risk of prostatitis in patients with type 2 diabetes mellitus: An observational retrospective cohort study of canagliflozin versus other antihyperglycemic agents using propensity score matching

Zhong Yuan,
Carolyn H. Jeffcoat,
Saberi Rana Ali,
Anthony G. Sena,
Martijn J. Schuemie,
Patrick B. Ryan,
Sergio A. Fonseca

Published: February 2, 2026
https://doi.org/10.1371/journal.pone.0341745

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