Precision screening identifies mitoxantrone as a multitarget inhibitor in ageing-associated cancers with extensive computational validation and doxorubicin comparison

• Mohammed H. Al-Qahtani ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: mhalqahtani@kau.edu.sa, qahtani_i@hotmail.com

  Affiliations Institute of Genomic Medicine Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Department of Medical Lab Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

  https://orcid.org/0009-0002-8237-9079

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• Mourad Assidi,

  Roles Conceptualization, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing – original draft

  Affiliations Institute of Genomic Medicine Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Department of Medical Lab Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

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• Abdelbaset Buhmeida,

  Roles Conceptualization, Investigation, Project administration, Software, Supervision, Validation, Writing – original draft

  Affiliations Institute of Genomic Medicine Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Department of Medical Lab Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

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• Asma Almuhammadi,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Resources, Supervision, Visualization, Writing – review & editing

  Affiliation Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, Saudi Arabia

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• Peter Natesan Pushparaj,

  Roles Data curation, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Institute of Genomic Medicine Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Department of Medical Lab Technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

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• Nofe Ateq Alganmi

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Resources, Software, Visualization, Writing – review & editing

  Affiliations Institute of Genomic Medicine Sciences, King Abdulaziz University, Jeddah, Saudi Arabia, Computer Science Department, Faculty of Computing and Information Technology, King Abdulaziz University, Jeddah, Saudi Arabia

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