Reduced masticatory stimuli modulate myokine secretion in the masseter muscle in mice

Marin Kawasaki; Chiho Kato; Moe Tanigawa; Eri Misawa; Keigo Nakamura; Haruka Inaba; Yasunori Abe; Satoshi Kokai; Takashi Ono

doi:10.1371/journal.pone.0341417

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Open Access

Peer-reviewed

Research Article

Reduced masticatory stimuli modulate myokine secretion in the masseter muscle in mice

Marin Kawasaki,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Visualization, Writing – review & editing

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan

https://orcid.org/0009-0003-0850-1985

⨯
Chiho Kato ,

* E-mail: katorts@tmd.ac.jp

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Moe Tanigawa,

Roles Conceptualization, Project administration

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Eri Misawa,

Roles Project administration

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Keigo Nakamura,

Roles Investigation

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Haruka Inaba,

Roles Project administration

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Yasunori Abe,

Roles Project administration

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Satoshi Kokai,

Roles Project administration

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯
Takashi Ono

Roles Project administration, Supervision, Writing – review & editing

Affiliation Department of Orthodontic Science, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan
⨯

Reduced masticatory stimuli modulate myokine secretion in the masseter muscle in mice

Marin Kawasaki,
Chiho Kato,
Moe Tanigawa,
Eri Misawa,
Keigo Nakamura,
Haruka Inaba,
Yasunori Abe,
Satoshi Kokai,
Takashi Ono

Published: January 29, 2026
https://doi.org/10.1371/journal.pone.0341417

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