A novel application tunnel in combination with medical training reduces stress induced by frequent intraperitoneal injections and blood draws in mice

• Anne Schlutt,

  Roles Data curation, Formal analysis, Investigation, Visualization, Writing – original draft

  Affiliations Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany, Taskforce Refinement, Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Katarina Riesner,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliations Taskforce Refinement, Charité - Universitätsmedizin Berlin, Berlin, Germany, Department of Hematology, Oncology and Tumorimmunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Merle Kochan,

  Roles Data curation, Writing – review & editing

  Affiliation Julius Wolff Institute, Charité - Universitätsmedizin Berlin and Berlin Institute of Health at Charité, Berlin, Germany

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• Ann-Kathrin Meß,

  Roles Data curation, Writing – review & editing

  Affiliation Julius Wolff Institute, Charité - Universitätsmedizin Berlin and Berlin Institute of Health at Charité, Berlin, Germany

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• Denise Jahn,

  Roles Data curation, Writing – review & editing

  Affiliations Taskforce Refinement, Charité - Universitätsmedizin Berlin, Berlin, Germany, Department of Oral and Maxillofacial Surgery, Charité - Universitätsmedizin Berlin, Berlin, Germany

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• Isabella Lurje,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany

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• Wiebke Werner,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany

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• Felix Heymann,

  Roles Methodology

  Affiliation Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany

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• Olivia Kershaw,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Institute of Veterinary Pathology, Freie Universität Berlin, Berlin, Germany

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• Frank Tacke,

  Roles Supervision, Writing – review & editing

  Affiliation Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany

  https://orcid.org/0000-0001-6206-0226

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• Bernhard Hiebl,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Institute of Animal Hygiene, Animal Welfare and Farm Animal Behaviour (ITTN), University of Veterinary Medicine Hannover, Hannover, Germany

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• Linda Hammerich

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Linda.hammerich@charite.de

  Affiliations Department of Hepatology and Gastroenterology, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum and Campus Charité Mitte, Berlin, Germany, Taskforce Refinement, Charité - Universitätsmedizin Berlin, Berlin, Germany

  https://orcid.org/0000-0003-0557-3927

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