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Open Access
Peer-reviewed
Research Article
JMJD3 regulates the M2-like macrophage polarization and promotes the growth of breast cancer cells via STAT6/IRF4 axis
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Juan Lyu,
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Writing – original draft
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Enqin Wang,
Roles Investigation
Affiliation Department of pathology, Wuchuan County People’s Hospital, Zunyi, Guizhou, P.R. China
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Shanmei Lyu,
Roles Methodology, Visualization
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Ying Qian,
Roles Funding acquisition, Methodology
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Fen Ye,
Roles Validation
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Xiuping Xu,
Roles Methodology
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Qing Wang,
Roles Validation
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Tao Lu,
Roles Validation
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Liangfeng Hu,
Roles Resources
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Hongkun Xu,
Roles Investigation
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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Lihong Zhang
Roles Conceptualization, Data curation, Resources, Supervision, Writing – review & editing
* E-mail: whb0575@163.com
Affiliations Department of Clinical Laboratory, Shaoxing People’s Hospital, Shaoxing, Zhejiang, P.R. China, School of Medicine, Shaoxing University, Shaoxing, Zhejiang, P.R. China
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JMJD3 regulates the M2-like macrophage polarization and promotes the growth of breast cancer cells via STAT6/IRF4 axis
- Juan Lyu,
- Enqin Wang,
- Shanmei Lyu,
- Ying Qian,
- Fen Ye,
- Xiuping Xu,
- Qing Wang,
- Tao Lu,
- Liangfeng Hu,
- Hongkun Xu
- Published: April 9, 2026
- https://doi.org/10.1371/journal.pone.0341313