Integrative genomic analysis reveals DHX58 as a key player in gastric cancer

Yan Li; Liren Zhang; Zhi Wen; Haixia Wang; Kunming Zhang; Buzai Wang; Jinfan Li; Huiqing Kang; Yanjun Gao; Zhi Yu; Yongzhe Du

doi:10.1371/journal.pone.0341230

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Open Access

Peer-reviewed

Research Article

Integrative genomic analysis reveals DHX58 as a key player in gastric cancer

Yan Li ,

Contributed equally to this work with: Yan Li, Liren Zhang

Roles Data curation, Investigation, Writing – original draft, Writing – review & editing

¶☯ Those authors are co-first authors and contributed equally to this study.

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China
⨯
Liren Zhang ,

Contributed equally to this work with: Yan Li, Liren Zhang

Roles Project administration, Resources

¶☯ Those authors are co-first authors and contributed equally to this study.

Affiliation Dispensary for Western Medicine, Wuhai People’s Hospital, Wuhai, China
⨯
Zhi Wen,

Roles Formal analysis

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China
⨯
Haixia Wang,

Roles Project administration

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China
⨯
Kunming Zhang,

Roles Investigation

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China
⨯
Buzai Wang ,

Roles Formal analysis, Investigation

* E-mail: wangbuzai2009@sina.com (BW); yongzheDu@126.com (YD)

Affiliation Department of Medical Imaging, Wuhai People’s Hospital, Wuhai, China
⨯
Jinfan Li,

Roles Investigation

Affiliation Department of Pathology, Wuhai People’s Hospital, Wuhai, China
⨯
Huiqing Kang,

Roles Formal analysis

Affiliation Department of Pathology, Wuhai People’s Hospital, Wuhai, China
⨯
Yanjun Gao,

Roles Formal analysis

Affiliation Department of Pathology, Wuhai People’s Hospital, Wuhai, China
⨯
Zhi Yu,

Roles Data curation, Investigation

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China
⨯
Yongzhe Du

Roles Conceptualization, Methodology, Project administration, Supervision, Validation

* E-mail: wangbuzai2009@sina.com (BW); yongzheDu@126.com (YD)

Affiliation Department of Gastroenterology, Wuhai People’s Hospital, Wuhai, China

https://orcid.org/0009-0005-4954-2729

⨯

Integrative genomic analysis reveals DHX58 as a key player in gastric cancer

Yan Li,
Liren Zhang,
Zhi Wen,
Haixia Wang,
Kunming Zhang,
Buzai Wang,
Jinfan Li,
Huiqing Kang,
Yanjun Gao,
Zhi Yu

Published: January 22, 2026
https://doi.org/10.1371/journal.pone.0341230

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