The novel mineralocorticoid receptor modulator balcinrenone protects against diet-induced cardiac microvascular dysfunction and plasma potassium elevation in mouse models

• Matthew J. Wolf,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Resources, Writing – review & editing

  Affiliation Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Soumaya El Moghrabi,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation INSERM, UMRS 1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France

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• Roberto Palacios-Ramirez,

  Roles Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Current Address: Unidad de Excelencia Instituto de Biología y Genética Molecular (IBGM), Universidad de Valladolid-CSIC, Valladolid, Spain

  Affiliation INSERM, UMRS 1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France

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• Krister Bamberg ,

  Roles Conceptualization, Data curation, Formal analysis, Resources, Writing – original draft, Writing – review & editing

  * E-mail: krister.bamberg@astrazeneca.com

  Affiliation Research and Early Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

  https://orcid.org/0000-0002-0538-6083

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• Leigh A. Bradley,

  Roles Investigation, Writing – review & editing

  Affiliation Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Frederick H. Epstein,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Visualization, Resources, Software, Writing – review & editing

  Affiliation Department of Medicine, University of Virginia, Charlottesville, Virginia, United States of America

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• Judith Hartleib-Geschwindner,

  Roles Conceptualization, Writing – original draft, Writing – review & editing

  Affiliation Late Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden

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• Frédéric Jaisser

  Roles Conceptualization, Formal analysis, Methodology, Resources, Visualization, Writing – original draft, Writing – review & editing

  Affiliations INSERM, UMRS 1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université de Paris, Paris, France, Université de Lorraine, INSERM Centre d’Investigations Cliniques-Plurithématique 1433, UMR 1116, CHRU de Nancy, French-Clinical Research, Infrastructure Network (F-CRIN) INI-CRCT, Nancy, France

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