Clinical proof of concept for small molecule mediated inhibition of IL-17 in psoriasis

• Richard B. Warren ,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ First author.

  Affiliations Dermatology Centre, Northern Care Alliance NHS Foundation Trust, Manchester, United Kingdom, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom

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• Hamish J. A. Hunter,

  Roles Conceptualization, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Dermatology Centre, Northern Care Alliance NHS Foundation Trust, Manchester, United Kingdom, NIHR Manchester Biomedical Research Centre, Manchester University NHS Foundation Trust, Manchester Academic Health Science Centre, Manchester, United Kingdom, Medicines Evaluation Unit, Manchester, United Kingdom

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• Kim A. Papp,

  Roles Conceptualization, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Alliance Clinical Research and Probity Medical Research, Waterloo, Ontario, Canada, Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Kenneth B. Gordon,

  Roles Conceptualization, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Dermatology, Medical College of Wisconsin, Wauwatosa, Wisconsin, United States of America

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• Meina T. Tang,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

  https://orcid.org/0000-0002-4787-742X

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• Jeffrey V. Enejosa,

  Roles Conceptualization, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Kuan-Chieh Huang,

  Roles Data curation, Formal analysis, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Debasish Raha,

  Roles Data curation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Hashini M. Batugedara,

  Roles Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

  https://orcid.org/0000-0001-6180-5505

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• Craig Skinner,

  Roles Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Philip A. Kobel,

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Peter M. Rademacher,

  Roles Investigation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• Nico Ghilardi ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: nico.ghilardi@lilly.com

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

  https://orcid.org/0000-0003-4945-3097

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• Paul Fatheree,

  Roles Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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• John R. Jacobsen,

  Roles Data curation, Formal analysis, Funding acquisition, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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•  [ ... ],
• Timothy T. Lu

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation DICE Therapeutics, a wholly owned subsidiary of Eli Lilly and Company, South San Francisco, California, United States of America

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