Evaluation of oxygenation indices incorporating SpO₂ and PEEP for assessing ARDS severity: Evidence from the MIMIC-IV and eICU collaborative research database v2.0 databases

Zekun Wei; Cunyang Li; Zhiyun Liu; Bolin Wang; Can Wang; Yang Liu; Tejin Ba; Li Kong; Feihu Zhang

doi:10.1371/journal.pone.0341004

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Open Access

Peer-reviewed

Research Article

Evaluation of oxygenation indices incorporating SpO₂ and PEEP for assessing ARDS severity: Evidence from the MIMIC-IV and eICU collaborative research database v2.0 databases

Zekun Wei ,

Contributed equally to this work with: Zekun Wei, Cunyang Li

Roles Formal analysis, Visualization, Writing – original draft

Affiliation The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Cunyang Li ,

Contributed equally to this work with: Zekun Wei, Cunyang Li

Roles Conceptualization, Validation

Affiliation The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Zhiyun Liu,

Roles Conceptualization

Affiliation The First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, China
⨯
Bolin Wang,

Roles Software

Affiliation Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China
⨯
Can Wang,

Roles Validation

Affiliation Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China
⨯
Yang Liu,

Roles Methodology

Affiliation Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China
⨯
Tejin Ba,

Roles Supervision

Affiliation Department of Emergency and Critical Care Medicine, International Mongolian Medical Hospital of Inner Mongolia Autonomous Region, Hohhot, China
⨯
Li Kong ,

Roles Writing – review & editing

* E-mail: zfh_1341@163.com (FZ); likongszy@126.com (LK)

Affiliation Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China

https://orcid.org/0009-0007-7267-2438

⨯
Feihu Zhang

Roles Writing – review & editing

* E-mail: zfh_1341@163.com (FZ); likongszy@126.com (LK)

Affiliation Department of Emergency Center, Shandong University of Traditional Chinese Medicine Affiliated Hospital, Jinan, China
⨯

Evaluation of oxygenation indices incorporating SpO₂ and PEEP for assessing ARDS severity: Evidence from the MIMIC-IV and eICU collaborative research database v2.0 databases

Zekun Wei,
Cunyang Li,
Zhiyun Liu,
Bolin Wang,
Can Wang,
Yang Liu,
Tejin Ba,
Li Kong,
Feihu Zhang

Published: February 5, 2026
https://doi.org/10.1371/journal.pone.0341004

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