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Open Access
Peer-reviewed
Research Article
Lipopolysaccharide induced mouse depression model can better simulate changes in peripheral blood FFAs in alMDD
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Jincai Pan ,
Contributed equally to this work with: Jincai Pan, Guanxi Liu
Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
¶☯ These authors contributed equally to this work.
Affiliations The First School of Clinical Medicine, Southern Medical University, Guangzhou, China, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Guanxi Liu ,
Contributed equally to this work with: Jincai Pan, Guanxi Liu
Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Supervision, Writing – review & editing
¶☯ These authors contributed equally to this work.
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Yuyuan Wang ,
Roles Data curation
¶‡ YW and YL also contributed equally to this work.
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Yuting Lan ,
Roles Data curation
¶‡ YW and YL also contributed equally to this work.
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Yanmei Liang,
Roles Data curation
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Weicheng Li,
Roles Data curation, Resources
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Kexin Zhu,
Roles Writing – review & editing
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Yanling Zhou ,
Roles Funding acquisition, Resources
* E-mail: zhouylivy@aliyun.com (YZ); ningjeny@126.com (YN)
Affiliations The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Yuping Ning
Roles Funding acquisition, Project administration
* E-mail: zhouylivy@aliyun.com (YZ); ningjeny@126.com (YN)
Affiliations The First School of Clinical Medicine, Southern Medical University, Guangzhou, China, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, China, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, Guangzhou Medical University, Guangzhou, China, Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders, Guangzhou, China
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Lipopolysaccharide induced mouse depression model can better simulate changes in peripheral blood FFAs in alMDD
- Jincai Pan,
- Guanxi Liu,
- Yuyuan Wang,
- Yuting Lan,
- Yanmei Liang,
- Weicheng Li,
- Kexin Zhu,
- Yanling Zhou,
- Yuping Ning
- Published: January 23, 2026
- https://doi.org/10.1371/journal.pone.0340967