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Open Access
Peer-reviewed
Research Article
Association of leukocyte count with death in people with HIV: A longitudinal study over 24 years
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Zoe Klein ,
Contributed equally to this work with: Zoe Klein, Sophia C. Meyer
Roles Conceptualization, Visualization, Writing – original draft, Writing – review & editing
* E-mail: philip.tarr@unibas.ch (PET); zoe.klein@stud.unibas.ch (ZK)
Affiliation University Center for Internal Medicine and Infectious Diseases Service, Kantonsspital Baselland, Department of Clinical Research, University Hospital Basel, University of Basel, Bruderholz, Switzerland
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Sophia C. Meyer ,
Contributed equally to this work with: Zoe Klein, Sophia C. Meyer
Roles Conceptualization, Writing – original draft, Writing – review & editing
Affiliation University Center for Internal Medicine and Infectious Diseases Service, Kantonsspital Baselland, Department of Clinical Research, University Hospital Basel, University of Basel, Bruderholz, Switzerland
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Isabella C. Schoepf,
Roles Writing – review & editing
Affiliations University Center for Internal Medicine and Infectious Diseases Service, Kantonsspital Baselland, Department of Clinical Research, University Hospital Basel, University of Basel, Bruderholz, Switzerland, Hepatology, Department for Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Bern, Switzerland
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Marc Weber,
Roles Writing – review & editing
Affiliation Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Christian W. Thorball,
Roles Writing – review & editing
Affiliation Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
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Lene Ryom,
Roles Writing – review & editing
Affiliations Centre of Excellence for Health, Immunity, and Infections, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark, Department of Infectious Diseases, Hvidovre University Hospital, Copenhagen, Denmark, Department of Clinical Medicine, University of Copenhagen, Denmark
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Neeltje A. Kootstra,
Roles Writing – review & editing
Affiliation Experimental Immunology, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands
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Peter Reiss,
Roles Writing – review & editing
Affiliation Amsterdam University Medical Centers, University of Amsterdam, Global Health, and Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands
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Dominique L. Braun,
Roles Writing – review & editing
Affiliations Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Zurich, Switzerland
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Maria C. Thurnheer,
Roles Writing – review & editing
Affiliation Department of Infectious Diseases, Bern University Hospital, University of Bern, Bern, Switzerland
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Catia Marzolini,
Roles Writing – review & editing
Affiliation Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Basel, Switzerland
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Christian R. Kahlert,
Roles Writing – review & editing
Affiliation Division of Infectious Diseases, Kantonsspital St Gallen, St. Gallen, Switzerland
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Enos Bernasconi,
Roles Writing – review & editing
Affiliation Division of Infectious Diseases, Ospedale Regionale Lugano, University of Geneva and Università della Svizzera italiana, Lugano, Switzerland
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Matthias Cavassini,
Roles Writing – review & editing
Affiliation Infectious Diseases Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland
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Annalisa Marinosci,
Roles Writing – review & editing
Affiliation Division of Infectious Disease, Geneva University Hospital, Geneva, Switzerland
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Jacques Fellay,
Roles Writing – review & editing
Affiliations Precision Medicine Unit, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, School of Life Sciences, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
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Roger D. Kouyos,
Roles Data curation, Writing – review & editing
Affiliations Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Zurich, Switzerland
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Huldrych F. Günthard,
Roles Data curation, Project administration, Supervision, Writing – review & editing
Affiliations Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland, Institute of Medical Virology, University of Zurich, Zurich, Zurich, Switzerland
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Bruno Ledergerber,
Roles Conceptualization, Data curation, Formal analysis, Methodology, Project administration, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing
Affiliation Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, University of Zurich, Zurich, Switzerland
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Philip E. Tarr ,
Roles Conceptualization, Data curation, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing
* E-mail: philip.tarr@unibas.ch (PET); zoe.klein@stud.unibas.ch (ZK)
Affiliation University Center for Internal Medicine and Infectious Diseases Service, Kantonsspital Baselland, Department of Clinical Research, University Hospital Basel, University of Basel, Bruderholz, Switzerland
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and the Swiss HIV Cohort Study
¶A complete membership of the author group can be found in the Acknowledgments
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Association of leukocyte count with death in people with HIV: A longitudinal study over 24 years
- Zoe Klein,
- Sophia C. Meyer,
- Isabella C. Schoepf,
- Marc Weber,
- Christian W. Thorball,
- Lene Ryom,
- Neeltje A. Kootstra,
- Peter Reiss,
- Dominique L. Braun,
- Maria C. Thurnheer
- Published: January 8, 2026
- https://doi.org/10.1371/journal.pone.0340678