Inhibition of TREM1 attenuates myocardial ischemia-reperfusion injury-induced cardiomyocyte pyroptosis by suppressing the activation of the NF-κB signaling pathway

• Xiaohui Xu ,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  ¶‡ XX and LC contributed equally to this work and share first authorship on this work.

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Liang Cai ,

  Roles Conceptualization, Methodology, Validation, Writing – review & editing

  ¶‡ XX and LC contributed equally to this work and share first authorship on this work.

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Xuan Dang,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Jianbin Han,

  Roles Formal analysis, Writing – review & editing

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Yan Kou,

  Roles Writing – review & editing

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Chunyan Rong,

  Roles Writing – review & editing

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

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• Junjie Kou

  Roles Supervision

  * E-mail: junjiekou@163.com

  Affiliations Department of Cardiology, The Second Affiliated Hospital of Harbin Medical University, Harbin, China, The Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin, Heilongjiang Province, China

  https://orcid.org/0000-0003-1052-787X

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