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Open Access

Peer-reviewed

Research Article

Suicide adverse events associated with zopiclone and eszopiclone: A pharmacovigilance analysis based on FAERS, JADER and CVARD

Yinpeng Xu,

Roles Investigation, Writing – original draft, Writing – review & editing

Affiliation Department of Pharmacy, Ninth People’s Hospital of Zhengzhou, Zhengzhou, Henan, China

https://orcid.org/0009-0000-2899-771X

⨯
Fang Li,

Roles Conceptualization, Data curation, Investigation, Methodology, Writing – review & editing

Affiliation Department of Pharmacy, Ninth People’s Hospital of Zhengzhou, Zhengzhou, Henan, China
⨯
Mei Zhang,

Roles Conceptualization, Data curation, Writing – review & editing

Affiliation Department of Pharmacy, Women and Infants Hospital of Zhengzhou, Zhengzhou, Henan, China
⨯
Li Huang

Roles Data curation, Investigation, Methodology, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: sunchenzhang@hhu.edu.cn

Affiliation Department of Pharmacy, Women and Infants Hospital of Zhengzhou, Zhengzhou, Henan, China

https://orcid.org/0009-0005-1719-8943

⨯

Suicide adverse events associated with zopiclone and eszopiclone: A pharmacovigilance analysis based on FAERS, JADER and CVARD

Yinpeng Xu,
Fang Li,
Mei Zhang,
Li Huang

x

Published: January 8, 2026
https://doi.org/10.1371/journal.pone.0340357

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Suicide
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Medical risk factors
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Self harm
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Immune receptor signaling
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Data mining
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