Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

• Dylan M. Lanser ,

  Contributed equally to this work with: Dylan M. Lanser, Adam Turner

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, School of Medicine, University of California, Davis, California, United States of America

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• Adam Turner ,

  Contributed equally to this work with: Dylan M. Lanser, Adam Turner

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

  Current address: Research and Development Team, GenEdit, South San Francisco, CA, USA

  Affiliation Department of Pharmacology, School of Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0009-0002-9392-014X

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• Noah Pacifici,

  Roles Conceptualization, Formal analysis, Methodology, Validation

  Affiliation Department of Biomedical Engineering, University of California, Davis, California, United States of America

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• Kiem Vu,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmacology, School of Medicine, University of California, Davis, California, United States of America

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• Jamal Lewis,

  Roles Conceptualization, Formal analysis, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Biomedical Engineering, University of California, Davis, California, United States of America, J. Crayton Pruitt Family Department of Biomedical Engineering, University of Florida, Gainesville, Florida, United States of America

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• Angie Gelli

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: acgelli@ucdavis.edu

  Affiliation Department of Pharmacology, School of Medicine, University of California, Davis, California, United States of America

  https://orcid.org/0000-0003-3351-0683

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