Exploration and discovery of treatment targets for primary biliary cholangitis based on plasma and cerebrospinal fluid proteomics: A multicenter mendelian randomization study

• Jianxin Xi ,

  Contributed equally to this work with: Jianxin Xi, Shengnan Wang

  Roles Software, Writing – original draft

  Affiliations Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China, China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China

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• Shengnan Wang ,

  Contributed equally to this work with: Jianxin Xi, Shengnan Wang

  Roles Conceptualization, Data curation, Software

  Affiliations Department of Neurology, The First Hospital of Jilin University, ChangChun, Jilin, China, Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China

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• Jie Chen,

  Roles Formal analysis, Visualization

  Affiliation Department of Radiology, The First Hospital of Jilin University, Chang Chun, Jilin, China

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• Jason Chi Shing Law,

  Roles Writing – review & editing

  Affiliation Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong SAR, China

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• Jianglong Wang,

  Roles Software, Writing – original draft

  Affiliation First Operating Room, The First Hospital of Jilin University, Changchun, Jilin, China

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• Guan Huei Lee,

  Roles Writing – review & editing

  Affiliation Division of Gastroenterology and Hepatology, Department of Surgery, National University Hospital Singapore, Singapore

  https://orcid.org/0000-0002-8652-6403

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• Zhongqi Fan,

  Roles Writing – original draft

  Affiliations Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China, China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China

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• Guoyue Lv ,

  Roles Conceptualization, Writing – original draft

  * E-mail: chenyuguo@jlu.edu.cn (YC); lvgy@jlu.edu.cn (GL)

  Affiliations Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China, China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China

  https://orcid.org/0000-0003-4656-4955

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• Yuguo Chen

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: chenyuguo@jlu.edu.cn (YC); lvgy@jlu.edu.cn (GL)

  Affiliations Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, ChangChun, Jilin, China, China-Singapore Belt and Road Joint Laboratory on Liver Disease Research, Changchun, China

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