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Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route
- Sara C. Johnston ,
- Anthony T. Ginnetti,
- Nancy A. Twenhafel,
- Sarah L. W. Norris,
- Shiying Chen,
- Josh L. Moore,
- Christopher W. Boyce,
- Ondraya M. Frick,
- Dave N. Dyer,
- Donald J. Marsh,
- Stephen C. Stevens,
- Walter F. Knapp,
- Kerry L. Berrier,
- Hui Wan,
- Gregory C. Adam,
- Timothy J. Hartingh,
- Heather L. Esham,
- Jimmy O. Fiallos,
- Eugene L. Blue,
- Willie B. Sifford,
- Jonathan D. Latty,
- Harold L. Mills,
- Nazira A. Alli,
- Ashley E. Piper,
- Aimee I. Goodson,
- J. Matthew Meinig,
- David B. Olsen,
- Linda A. Lieberman ,
- [ ... ],
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Rekha G. Panchal
Contributed equally to this work with: Linda A. Lieberman, Rekha G. Panchal
Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Writing – original draft, Writing – review & editing
* E-mail: sara.c.johnston2.civ@health.mil (SCJ); rekha.g.panchal.civ@health.mil (RGP)
Affiliation Molecular Biology Division, United States of America Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America
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https://orcid.org/0000-0001-8621-9078
Efficacy evaluation of the S-adenosylhomocysteine hydrolase inhibitor MSD-914 in rhesus macaques (Macaca Mulatta) challenged with Ebola virus by the intramuscular route
- Sara C. Johnston,
- Anthony T. Ginnetti,
- Nancy A. Twenhafel,
- Sarah L. W. Norris,
- Shiying Chen,
- Josh L. Moore,
- Christopher W. Boyce,
- Ondraya M. Frick,
- Dave N. Dyer,
- Donald J. Marsh
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- Published: February 6, 2026
- https://doi.org/10.1371/journal.pone.0340118