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Open Access
Peer-reviewed
Research Article
Elevated anti-apoptotic shift in primary human aniridia limbal stromal cells following 48 hours supraphysiological glucose exposure, in vitro
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Shanhe Liu ,
Roles Data curation, Formal analysis, Funding acquisition, Software, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: liushanhe666@gmail.com
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Shuailin Li,
Roles Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Shao-Lun Hsu,
Roles Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Fabian N. Fries,
Roles Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany
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Zhen Li,
Roles Writing – review & editing
Affiliation Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany
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Swarnali Kundu,
Roles Writing – review & editing
Affiliation Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany
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Berthold Seitz,
Roles Funding acquisition, Writing – review & editing
Affiliation Department of Ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany
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Maryam Amini,
Roles Writing – review & editing
Affiliation Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany
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Shweta Suiwal,
Roles Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Tanja Stachon,
Roles Conceptualization, Methodology, Project administration, Supervision, Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Nóra Szentmáry
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Writing – original draft, Writing – review & editing
Affiliations Dr. Rolf M. Schwiete Center for Limbal Stem Cell and Congenital Aniridia Research, Saarland University, Homburg, Saarland, Germany, Department of Experimental Ophthalmology, Saarland University, Homburg, Saarland, Germany
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Elevated anti-apoptotic shift in primary human aniridia limbal stromal cells following 48 hours supraphysiological glucose exposure, in vitro
- Shanhe Liu,
- Shuailin Li,
- Shao-Lun Hsu,
- Fabian N. Fries,
- Zhen Li,
- Swarnali Kundu,
- Berthold Seitz,
- Maryam Amini,
- Shweta Suiwal,
- Tanja Stachon
- Published: January 12, 2026
- https://doi.org/10.1371/journal.pone.0340117