Prognostic value of tumor deposits and their different response to neoadjuvant therapy in locally advanced rectal cancer

Di Zhou; Junjun Zhou; Bin Hu; Yinjue Yu; Yuhai Bian; Cuiping Yang; Yongrui Bai; Haiyan Chen

doi:10.1371/journal.pone.0340000

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Open Access

Peer-reviewed

Research Article

Prognostic value of tumor deposits and their different response to neoadjuvant therapy in locally advanced rectal cancer

Di Zhou ,

Contributed equally to this work with: Di Zhou

Roles Writing – original draft, Writing – review & editing

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

https://orcid.org/0000-0001-9714-2993

⨯
Junjun Zhou ,

Roles Conceptualization, Data curation

¶‡ These authors also contributed equally to this work.

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Bin Hu ,

Roles Formal analysis, Funding acquisition

¶‡ These authors also contributed equally to this work.

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Yinjue Yu ,

Roles Methodology, Software, Supervision

¶‡ These authors also contributed equally to this work.

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Yuhai Bian ,

Roles Project administration, Resources

¶‡ These authors also contributed equally to this work.

Affiliation Department of Gastrointestinal Surgery, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Cuiping Yang ,

Roles Software, Supervision, Validation

¶‡ These authors also contributed equally to this work.

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Yongrui Bai ,

Roles Conceptualization, Supervision

¶‡ These authors also contributed equally to this work.

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯
Haiyan Chen

Roles Conceptualization, Writing – review & editing

* E-mail: chenhaiyan1220@163.com

Affiliation Department of Radiation Oncology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
⨯

Prognostic value of tumor deposits and their different response to neoadjuvant therapy in locally advanced rectal cancer

Di Zhou,
Junjun Zhou,
Bin Hu,
Yinjue Yu,
Yuhai Bian,
Cuiping Yang,
Yongrui Bai,
Haiyan Chen

Published: January 13, 2026
https://doi.org/10.1371/journal.pone.0340000

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