Safety and therapeutic potential evaluation of Cefotaxime plus Polymyxin B against polymyxin-carbapenem resistant Klebsiella pneumoniae in a murine model

• Mariana Carvalho Sturaro,

  Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Nathalia da Silva Damaceno,

  Roles Investigation

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Gleyce Hellen de Almeida de Souza,

  Roles Investigation, Writing – review & editing

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• José Eduardo Souza Echeverria,

  Roles Investigation

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Ediane Bortolotte Cornelius,

  Roles Investigation, Methodology

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Luccas Pereira Pires,

  Roles Investigation

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Pedro Vinícius Dias Bassetto Silva,

  Roles Formal analysis

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Bárbara Maria Cristaldo Gomes,

  Roles Investigation

  Affiliation University Center of Grande Dourados – UNIGRAN, Dourados, Mato Grosso do Sul, Brazil

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• Thiago Leite Fraga,

  Roles Methodology, Writing – review & editing

  Affiliation University Center of Grande Dourados – UNIGRAN, Dourados, Mato Grosso do Sul, Brazil

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• Osmar Nascimento Silva,

  Roles Writing – review & editing

  Affiliation Evangelical University of Goiás, Anápolis, Goiás, Brazil

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• Luana Rossato,

  Roles Writing – review & editing

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

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• Simone Simionatto

  Roles Conceptualization, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: simonesimionatto@ufgd.edu.br

  Affiliation Laboratory of Research in Health Science, Federal University of Grande Dourados, Dourados, Mato Grosso do Sul, Brazil

  https://orcid.org/0000-0003-2367-0915

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