The immune checkpoint inhibitor avelumab increases aortic inflammation on [¹⁸F]FDG PET/CT: A retrospective cohort study

• Anniek Strijdhorst ,

  Contributed equally to this work with: Anniek Strijdhorst, Reindert F. Oostveen, Margot Tesselaar, Hein J. Verberne, Nick van Es

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

  * E-mail: a.strijdhorst@amsterdamumc.nl

  Affiliations Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands, Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, The Netherlands, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, The Netherlands

  https://orcid.org/0009-0009-8033-7298

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• Reindert F. Oostveen ,

  Contributed equally to this work with: Anniek Strijdhorst, Reindert F. Oostveen, Margot Tesselaar, Hein J. Verberne, Nick van Es

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Software, Visualization, Writing – original draft

  Affiliations Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, The Netherlands

  ⨯
• Mark P.A. Schilder,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands

  https://orcid.org/0009-0007-8656-6687

  ⨯
• Arthur J.A.T. Braat,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Nuclear Medicine, The Netherlands Cancer Institute—Antoni van Leeuwenhoek, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-8824-8697

  ⨯
• Youssef Chahid,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

  https://orcid.org/0000-0002-6223-3454

  ⨯
• Damini Dey,

  Roles Conceptualization, Software, Writing – review & editing

  Affiliation Department of Medicine (Division of Artificial Intelligence), Cedars-Sinai Medical Center, Los Angeles, California, United States of America

  ⨯
• Nordin M.J. Hanssen,

  Roles Conceptualization, Writing – review & editing

  Affiliations Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, The Netherlands

  ⨯
• Hanneke W.M. van Laarhoven,

  Roles Conceptualization, Writing – review & editing

  Affiliations Cancer Center Amsterdam, Cancer Treatment and Quality of Life, Amsterdam, The Netherlands, Amsterdam University Medical Center, location University of Amsterdam, Department of Medical Oncology, Amsterdam, the Netherlands

  ⨯
• Anne W. van Schijndel,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Intensive Care, The Netherlands Cancer Institute—Antoni van Leeuwenhoek, Amsterdam, The Netherlands, Department of Cardiology, The Netherlands Cancer Institute—Antoni van Leeuwenhoek, Amsterdam, the Netherlands

  ⨯
• Tom T.P. Seijkens,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliation Division of Medical Oncology, The Netherlands Cancer Institute—Antoni van Leeuwenhoek, Amsterdam, the Netherlands

  ⨯
• Piotr J. Slomka,

  Roles Conceptualization, Software, Writing – review & editing

  Affiliation Department of Medicine (Division of Artificial Intelligence), Cedars-Sinai Medical Center, Los Angeles, California, United States of America

  ⨯
• Erik S.G. Stroes,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, The Netherlands

  ⨯
• Margot Tesselaar ,

  Contributed equally to this work with: Anniek Strijdhorst, Reindert F. Oostveen, Margot Tesselaar, Hein J. Verberne, Nick van Es

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Division of Medical Oncology, The Netherlands Cancer Institute—Antoni van Leeuwenhoek, Amsterdam, the Netherlands

  ⨯
• Hein J. Verberne ,

  Contributed equally to this work with: Anniek Strijdhorst, Reindert F. Oostveen, Margot Tesselaar, Hein J. Verberne, Nick van Es

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliation Department of Radiology and Nuclear Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands

  ⨯
• Nick van Es

  Contributed equally to this work with: Anniek Strijdhorst, Reindert F. Oostveen, Margot Tesselaar, Hein J. Verberne, Nick van Es

  Roles Conceptualization, Methodology, Supervision, Writing – review & editing

  Affiliations Amsterdam University Medical Center, location University of Amsterdam, Department of Vascular Medicine, Amsterdam, The Netherlands, Amsterdam Cardiovascular Sciences, Atherosclerosis & Ischemic Syndromes, Amsterdam, The Netherlands

  ⨯