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Open Access
Peer-reviewed
Research Article
Rethinking procedural pain in labor: A comparison of lidocaine injection techniques for epidural catheter placement assessed with an objective clinician-centric pain score—A double-blind randomized controlled trial
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Lukas Croner ,
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Data curation, Validation, Writing – original draft, Writing – review & editing
Affiliation College of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Plato Lysandrou ,
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Conceptualization, Investigation, Methodology, Writing – review & editing
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Haosheng Li ,
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Data curation, Funding acquisition, Validation, Writing – review & editing
Affiliation College of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Andrew Devine ,
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Data curation, Funding acquisition, Writing – review & editing
Affiliation Heritage College of Osteopathic Medicine, Ohio University, Athens, Ohio, United States of America
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Tyler Balon ,
Roles Investigation, Methodology, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation College of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Yun Xia ,
Roles Investigation, Methodology, Supervision, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Nasir Hussain ,
Roles Methodology, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Yue Yu ,
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Data curation, Formal analysis, Software, Validation, Writing – review & editing
Affiliation Center for Biostatistics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Mahmoud Abdel-Rasoul ,
Roles Data curation, Formal analysis, Software, Supervision, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Center for Biostatistics, College of Medicine, The Ohio State University, Columbus, Ohio, United States of America
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Marco Echeverria Villalobos ,
Roles Funding acquisition, Resources, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Alberto Uribe ,
Roles Project administration, Resources, Visualization, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Elvia Vera Miquilena ,
Roles Data curation, Validation, Writing – review & editing
¶‡ TB, YX, NH, MA-R, MEV, AU and EVM also contributed equally to this work.
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Ling-Qun Hu
Contributed equally to this work with: Lukas Croner, Plato Lysandrou, Haosheng Li, Andrew Devine, Yue Yu, Ling-Qun Hu
Roles Conceptualization, Data curation, Investigation, Methodology, Supervision, Writing – review & editing
* E-mail: lingqun.hu@osumc.edu
Affiliation Department of Anesthesiology, The Ohio State University College of Medicine, Columbus, Ohio, United States of America
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Rethinking procedural pain in labor: A comparison of lidocaine injection techniques for epidural catheter placement assessed with an objective clinician-centric pain score—A double-blind randomized controlled trial
- Lukas Croner,
- Plato Lysandrou,
- Haosheng Li,
- Andrew Devine,
- Tyler Balon,
- Yun Xia,
- Nasir Hussain,
- Yue Yu,
- Mahmoud Abdel-Rasoul,
- Marco Echeverria Villalobos
- Published: February 11, 2026
- https://doi.org/10.1371/journal.pone.0339664