Development of a CYP2D6-enhanced HepaRG cell model with improved CYP2D6 metabolic capacity

• Chizuka Obara,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

  Affiliation Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan

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• Yohei Iizaka,

  Roles Investigation, Writing – original draft

  Affiliation Department of Microbiology, Faculty of Pharmaceutical Sciences, Toho University, Japan

  https://orcid.org/0000-0002-5951-4511

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• Akari Mine,

  Roles Investigation

  Affiliation Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan

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• Yojiro Anzai,

  Roles Supervision

  Affiliation Department of Microbiology, Faculty of Pharmaceutical Sciences, Toho University, Japan

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• Masako Tada ,

  Roles Conceptualization

  ¶Deceased 21 October 2023.

  ¶‡ MT and SY shared senior co-authorship.

  Affiliation Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan

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• Shinpei Yamaguchi

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  * E-mail: shinpei.yamaguchi@sci.toho-u.ac.jp

  ¶‡ MT and SY shared senior co-authorship.

  Affiliation Stem Cells and Reprogramming Laboratory, Department of Biology, Faculty of Science, Toho University, Funabashi, Chiba, Japan

  https://orcid.org/0000-0002-9377-4835

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