Does randomization matter in rare disease clinical trials

• Stephanie Wied ,

  Roles Conceptualization, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: stephanie.wied@rwth-aachen.de

  Affiliations Institute of Medical Statistics, RWTH Aachen University, Aachen, Germany, Medical Faculty, Sigmund Freud Private University, Vienna, Austria

  https://orcid.org/0000-0003-0616-6610

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• Denis Kirilov Razsolkov,

  Roles Software, Validation, Writing – review & editing

  Affiliation Institute of Medical Statistics, RWTH Aachen University, Aachen, Germany

  https://orcid.org/0009-0003-4273-1100

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• Nicole Heussen,

  Roles Funding acquisition, Methodology, Writing – review & editing

  Affiliations Institute of Medical Statistics, RWTH Aachen University, Aachen, Germany, Medical Faculty, Sigmund Freud Private University, Vienna, Austria

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• Ralf-Dieter Hilgers

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Institute of Medical Statistics, RWTH Aachen University, Aachen, Germany, Medical Faculty, Sigmund Freud Private University, Vienna, Austria

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