Gender differences in the association between pan-immune-inflammation value and probable depression: A cross-sectional study

Dongdong Yu; Ting Cheng; Yue Yang; Xingying Qiu; Geng Li; Li Zhou; Zehuai Wen

doi:10.1371/journal.pone.0339348

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Open Access

Peer-reviewed

Research Article

Gender differences in the association between pan-immune-inflammation value and probable depression: A cross-sectional study

Dongdong Yu ,

Contributed equally to this work with: Dongdong Yu, Ting Cheng

Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

Affiliation Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China

https://orcid.org/0000-0003-2759-7647

⨯
Ting Cheng ,

Contributed equally to this work with: Dongdong Yu, Ting Cheng

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliations Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China
⨯
Yue Yang,

Roles Validation, Visualization

Affiliation First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, China
⨯
Xingying Qiu,

Roles Validation, Visualization

Affiliation Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Geng Li,

Roles Validation, Visualization

Affiliation Center for Clinical Research of Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Li Zhou,

Roles Validation, Visualization

Affiliation Center for Clinical Research of Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China
⨯
Zehuai Wen

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: wenzh@gzucm.edu.cn

Affiliations Center for Clinical Research of Guangdong Provincial Hospital of Chinese Medicine, Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China, Science and Technology Innovation Center of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China

https://orcid.org/0000-0002-1797-2047

⨯

Gender differences in the association between pan-immune-inflammation value and probable depression: A cross-sectional study

Dongdong Yu,
Ting Cheng,
Yue Yang,
Xingying Qiu,
Geng Li,
Li Zhou,
Zehuai Wen

Published: December 30, 2025
https://doi.org/10.1371/journal.pone.0339348

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