Emphasizing the role of oxidative stress and Sirt-1/Nrf2 and TLR-4/NF-κB in Tamarix aphylla mediated neuroprotective potential in rotenone-induced Parkinson’s disease: In silico and in vivo study

• Dalia H. Abu-Baih,

  Roles Conceptualization, Methodology, Writing – original draft

  Affiliations Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Deraya University, New Minia City, Minia, Egypt, Deraya Center for Scientific Research, Deraya University, New Minia City, Minia, Egypt

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• Abeer H. Elmaidomy,

  Roles Conceptualization, Investigation, Methodology, Validation, Writing – original draft

  Affiliation Department of Pharmacognosy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt

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• Hesham A. Abou-Zied,

  Roles Data curation, Formal analysis, Resources, Software, Writing – original draft

  Affiliation Department of Medicinal Chemistry, Faculty of Pharmacy, Deraya University, Minia, Egypt

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• Nahla Abdelghany Hussien,

  Roles Methodology, Resources

  Affiliation Deraya Center for Scientific Research, Deraya University, New Minia City, Minia, Egypt

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• Manar I. Rasekh,

  Roles Resources

  Affiliation Deraya Center for Scientific Research, Deraya University, New Minia City, Minia, Egypt

  ⨯
• Entesar A. Saber,

  Roles Conceptualization, Data curation, Methodology, Writing – original draft

  Affiliation Department of Medical Science, Histology and Cell Biology, Faculty of Pharmacy, Deraya University, New Minia City, Minia, Egypt

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• Sayed Fouad El-sheikh Ali,

  Roles Conceptualization, Data curation, Investigation, Writing – original draft

  Affiliation Department of Anatomy, Faculty of Medicine, Minia University, Minia, Egypt

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• Mostafa E. Rateb,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Natural and Medical Sciences Research Center, University of Nizwa, Nizwa, Oman

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• Omnia Magdy Hendawy,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Pharmacology, College of Pharmacy, Jouf University, Skaka, Saudi Arabia, Department of Clinical Pharmacology, College of Medicine, Beni-Suef University, Beni-Suef, Egypt

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• Faisal H. Altemani,

  Roles Conceptualization, Investigation, Writing – original draft

  Affiliation Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia

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• Abdullah H. Altemani,

  Roles Investigation, Methodology, Writing – original draft

  Affiliation Department of Family and Community Medicine, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia

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• Gerhard Bringmann,

  Roles Writing – review & editing

  Affiliation Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany

  https://orcid.org/0000-0002-3583-5935

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• Usama Ramadan Abdelmohsen ,

  Roles Conceptualization, Investigation, Methodology, Writing – review & editing

  * E-mail: usama.ramadan@mu.edu.eg (URA); omnia.hesham@deraya.edu.eg (OHA)

  Affiliations Deraya Center for Scientific Research, Deraya University, New Minia City, Minia, Egypt, Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia, Egypt

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• Omnia Hesham Abdelhafez

  Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Writing – original draft

  * E-mail: usama.ramadan@mu.edu.eg (URA); omnia.hesham@deraya.edu.eg (OHA)

  Affiliation Department of Pharmacognosy, Faculty of Pharmacy, Deraya University, New Minia, Egypt

  https://orcid.org/0000-0002-6362-9266

  ⨯