Integrative multi-omics analyses identify key genes and elucidate bidirectional regulatory mechanisms in thyroid dysfunction

• Yilang Hu ,

  Contributed equally to this work with: Yilang Hu, Hong Hu

  Roles Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft

  Affiliations Department of thyroid and breast surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong City, Jiangsu Province, China, Department of Medicine, Xinglin College, Nantong University, Nantong City, Jiangsu Province, China

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• Hong Hu ,

  Contributed equally to this work with: Yilang Hu, Hong Hu

  Roles Formal analysis, Methodology, Software, Validation, Writing – original draft, Data curation

  Affiliation Department of Medicine, Xinglin College, Nantong University, Nantong City, Jiangsu Province, China

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• Lijun Xu,

  Roles Project administration, Data curation

  Affiliation Department of thyroid and breast surgery, Changshu Hospital Affiliated to Nanjing University of Chinese Medicine, Suzhou City, Jiangsu Province, China

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• Xuzheng Tang,

  Roles Project administration

  Affiliation Department of Medicine, Xinglin College, Nantong University, Nantong City, Jiangsu Province, China

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• Chongyu Wang,

  Roles Software, Resources

  Affiliation Department of Medicine, Xinglin College, Nantong University, Nantong City, Jiangsu Province, China

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• Zhengyi Lian,

  Roles Project administration

  Affiliations Department of thyroid and breast surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong City, Jiangsu Province, China, Medical School of Nantong University, Nantong City, Jiangsu Province, China

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• Chenyu Xie,

  Roles Visualization

  Affiliation Medical School of Nantong University, Nantong City, Jiangsu Province, China

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• Zhiwan Xie,

  Roles Software

  Affiliation Department of Medicine, Xinglin College, Nantong University, Nantong City, Jiangsu Province, China

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• Qingqing Wang

  Roles Data curation, Formal analysis, Funding acquisition, Investigation, Resources, Supervision, Visualization, Conceptualization

  * E-mail: 5200130@ntu.edu.cn

  Affiliations Department of thyroid and breast surgery, Affiliated Hospital of Nantong University, Medical School of Nantong University, Nantong City, Jiangsu Province, China, Medical School of Nantong University, Nantong City, Jiangsu Province, China

  https://orcid.org/0009-0008-8235-9346

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