Optimizing expanded carrier screening for China: Multi-center study establishes 202-gene panel with optimal cost-effectiveness in preconception and prenatal care

• Yulu Yang ,

  Contributed equally to this work with: Yulu Yang, Yuting Hang

  Roles Data curation, Writing – original draft, Writing – review & editing

  Affiliations Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China, Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China

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• Yuting Hang ,

  Contributed equally to this work with: Yulu Yang, Yuting Hang

  Roles Data curation, Writing – original draft

  Affiliations Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China, Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China

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• WeiSheng Cheng,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China, Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China

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• Yunxia Cao,

  Roles Methodology, Project administration

  Affiliations Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China, Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China

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• Zhaolian Wei ,

  Roles Methodology, Writing – review & editing

  * E-mail: weizhaolian_1@126.com (ZW); yuanjing_ahmu@163.com (JY)

  Affiliations Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China, NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei, Anhui, China, Engineering Research Center of Biopreservation and Artificial Organs, Ministry of Education, Hefei, Anhui, China

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• Jing Yuan

  Roles Funding acquisition, Methodology

  * E-mail: weizhaolian_1@126.com (ZW); yuanjing_ahmu@163.com (JY)

  Affiliation Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China

  https://orcid.org/0000-0001-6054-8471

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