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Open Access

Peer-reviewed

Research Article

Activation and DNA methylation of PANoptosis in polycystic ovary syndrome

Yaguang Han,

Roles Writing – original draft

Affiliation The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Yanhua Han,

Roles Data curation

Affiliation The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Yuenan Feng,

Roles Data curation

Affiliation Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Yuanli Shan,

Roles Methodology

Affiliation The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Chang Liu,

Roles Validation

Affiliation Department of Traditional Chinese Medicine, Beijing University Third Hospital, Beijing, China
⨯
Kexin Wang,

Roles Methodology

Affiliation Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Xiaoke Li,

Roles Data curation

Affiliation Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Shidi Zhang,

Roles Data curation

Affiliation Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China
⨯
Xiaolin Zhu

Roles Writing – review & editing

* E-mail: 13845156909@126.com

Affiliation The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, Heilongjiang, China

https://orcid.org/0009-0001-1599-2626

⨯

Activation and DNA methylation of PANoptosis in polycystic ovary syndrome

Yaguang Han,
Yanhua Han,
Yuenan Feng,
Yuanli Shan,
Chang Liu,
Kexin Wang,
Xiaoke Li,
Shidi Zhang,
Xiaolin Zhu

x

Published: January 5, 2026
https://doi.org/10.1371/journal.pone.0338342

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Polycystic ovary syndrome
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DNA methylation
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Apoptosis
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Gene expression
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Inflammation
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Granulosa cells
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Methylation
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Stress signaling cascade
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