Blood RNA biomarkers and a point-of-care elastase assay for detecting host immune activation in suspected sepsis: Trajectory matters

• John E. Lafleur,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

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• Eduard Shaykhinurov,

  Roles Data curation, Investigation, Methodology, Project administration

  Affiliation Department of Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC,

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• John Perkins,

  Roles Data curation, Investigation, Methodology, Project administration, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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• Richard Wargowsky,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Validation, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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• Kevin Jaatinen,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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• Mary Pasquale,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

  https://orcid.org/0000-0003-0258-7194

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• Grace Holloway,

  Roles Data curation, Investigation, Validation, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

  https://orcid.org/0009-0006-0823-5076

  ⨯
• David Yamane,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliations Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,, Department of Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC,

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• Akhil Patel,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Daniel King,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration

  Affiliation Department of Anesthesiology and Critical Care Medicine, The George Washington University Medical Center, Washington, DC,

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• Andrew Meltzer,

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Ryan Heidish,

  Roles Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Soroush Shahamatdar,

  Roles Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Aditya Loganathan,

  Roles Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Tarun Loganathan,

  Roles Data curation, Investigation, Methodology, Project administration, Supervision

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Taylor Bolden,

  Roles Data curation, Investigation, Methodology

  Affiliation Department of Emergency Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Michael Zane Hayden,

  Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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• Aditya Maddali,

  Roles Data curation, Investigation

  Affiliation Department of Medicine, The George Washington University Medical Center, Washington, District of Columbia

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• Jennifer Goldman,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

  https://orcid.org/0000-0003-2651-8767

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• Zachary Falk,

  Roles Data curation, Investigation, Methodology, Validation

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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• Tisha Jepson,

  Roles Data curation, Project administration, Supervision, Visualization

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

  ⨯
• Avery League,

  Roles Data curation, Formal analysis, Validation, Visualization, Writing – review & editing

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

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•  [ ... ],
• Timothy A. McCaffrey

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: mcc@gwu.edu

  Affiliation Department of Medicine, Division of Genomic Medicine, The George Washington University Medical Center, Washington, DC,

  https://orcid.org/0000-0002-4648-7833

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