Temperature-humidity synergistic effects on predominant intestinal infectious diseases in Shenzhen, China: A predictive modeling framework for epidemiological early warning systems

Hongxin Lyu; Zhen Zhang; Haozheng Zhou; Yan Ren; Minhua Chen; Yu Zeng; Yanpeng Cheng; Huawei Xiong

doi:10.1371/journal.pone.0337929

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Open Access

Peer-reviewed

Research Article

Temperature-humidity synergistic effects on predominant intestinal infectious diseases in Shenzhen, China: A predictive modeling framework for epidemiological early warning systems

Hongxin Lyu,

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Writing – original draft

Affiliation Department of Epidemiology and Infectious Disease Control, Shenzhen Longhua Center for Disease Control and Prevention, Shenzhen, Guangdong, China

https://orcid.org/0000-0002-9634-2616

⨯
Zhen Zhang ,

Roles Funding acquisition, Supervision, Validation

* E-mail: 447574221@qq.com (HX); 471769761@qq.com (ZZ)

Affiliation Department of Infectious Disease Prevention and Control, Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Haozheng Zhou,

Roles Software

Affiliation School of Public Health, Southern Medical University, Guangzhou, Guangdong, China
⨯
Yan Ren,

Roles Investigation

Affiliation Department of Epidemiology and Infectious Disease Control, Shenzhen Longhua Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Minhua Chen,

Roles Visualization

Affiliation Department of Epidemiology and Infectious Disease Control, Shenzhen Longhua Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Yu Zeng,

Roles Methodology, Software

Affiliation Department of Epidemiology, Shenzhen Longgang Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Yanpeng Cheng,

Roles Resources

Affiliation Department of Infectious Disease Prevention and Control, Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China
⨯
Huawei Xiong

Roles Data curation, Funding acquisition, Supervision, Writing – review & editing

* E-mail: 447574221@qq.com (HX); 471769761@qq.com (ZZ)

Affiliation Department of Infectious Disease Prevention and Control, Shenzhen Center for Disease Control and Prevention, Shenzhen, Guangdong, China

https://orcid.org/0009-0003-9982-3225

⨯

Temperature-humidity synergistic effects on predominant intestinal infectious diseases in Shenzhen, China: A predictive modeling framework for epidemiological early warning systems

Hongxin Lyu,
Zhen Zhang,
Haozheng Zhou,
Yan Ren,
Minhua Chen,
Yu Zeng,
Yanpeng Cheng,
Huawei Xiong

Published: December 5, 2025
https://doi.org/10.1371/journal.pone.0337929

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