Chronic oral cannabidiol delays seizure onset and reduces seizure burden in a mouse model of CLN2 disease

• Joshua T. Dearborn ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: joshua.dearborn@wustl.edu

  Affiliations Department of Medicine, Washington University in St. Louis, St. Louis Missouri, United States of America, Department of Pediatrics, Washington University in St. Louis, St. Louis Missouri, United States of America

  https://orcid.org/0000-0003-0335-1087

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• Keigo Takahashi,

  Roles Investigation, Writing – original draft

  Affiliation Department of Pediatrics, Washington University in St. Louis, St. Louis Missouri, United States of America

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• Nicholas R. Rensing,

  Roles Data curation, Formal analysis, Investigation, Writing – original draft

  Affiliation Department of Neurology, Washington University in St. Louis, St. Louis Missouri, United States of America

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• Michael Wong,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Neurology, Washington University in St. Louis, St. Louis Missouri, United States of America

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• Jonathan D. Cooper,

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Pediatrics, Washington University in St. Louis, St. Louis Missouri, United States of America, Department of Neurology, Washington University in St. Louis, St. Louis Missouri, United States of America, Department of Genetics, Washington University in St. Louis, St. Louis Missouri, United States of America

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• Mark S. Sands

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Department of Medicine, Washington University in St. Louis, St. Louis Missouri, United States of America, Department of Genetics, Washington University in St. Louis, St. Louis Missouri, United States of America

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