Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella; Daniele Brambilla; Sara Surini; Diletta Tonoli; Lucrezia Maria Ribolla; Ivan de Curtis

doi:10.1371/journal.pone.0337621

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Open Access

Peer-reviewed

Research Article

Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy

https://orcid.org/0000-0003-3681-2847

⨯
Daniele Brambilla,

Roles Investigation, Methodology

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy
⨯
Sara Surini,

Roles Investigation, Methodology

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy

https://orcid.org/0000-0001-9366-7039

⨯
Diletta Tonoli,

Roles Investigation, Methodology

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy
⨯
Lucrezia Maria Ribolla,

Roles Investigation, Methodology

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy

https://orcid.org/0000-0002-3540-174X

⨯
Ivan de Curtis

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: decurtis.ivan@hsr.it

Affiliations Vita-Salute San Raffaele University, Milan, Italy, Cell Adhesion Unit, Division of Neuroscience, IRCCS San Raffaele Scientific Institute, Milan, Italy

https://orcid.org/0000-0002-7651-1515

⨯

Potential phosphorylation of Liprin-α1 at threonine 701 regulates integrin-mediated cell motility

Martina Ramella,
Daniele Brambilla,
Sara Surini,
Diletta Tonoli,
Lucrezia Maria Ribolla,
Ivan de Curtis

Published: December 1, 2025
https://doi.org/10.1371/journal.pone.0337621

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Phosphorylation
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Transfection
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Cell motility
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Immunoblotting
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Membrane proteins
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Immunofluorescence
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Substitution mutation
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Immunostaining
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