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Open Access

Peer-reviewed

Research Article

Molecular mechanism of gallium nitrate in inhibiting bacterial biofilm formation through pykF modulation

Xiaofeng Zhang,

Roles Conceptualization

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Junjie Dong ,

Roles Data curation

* E-mail: kmdjj1223@163.com (JD); 554879537@qq.com (JY)

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China

https://orcid.org/0009-0003-5383-982X

⨯
Bing Wang,

Roles Formal analysis

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Lingqiang Chen,

Roles Funding acquisition

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Zhiqiang Gong,

Roles Investigation

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Jin Yang ,

Roles Project administration

* E-mail: kmdjj1223@163.com (JD); 554879537@qq.com (JY)

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Guizhao Shu,

Roles Resources

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯
Qi Ning

Roles Validation

Affiliation The First Affiliated Hospital of Kunming Medical University, Kunming, China
⨯

Molecular mechanism of gallium nitrate in inhibiting bacterial biofilm formation through pykF modulation

Xiaofeng Zhang,
Junjie Dong,
Bing Wang,
Lingqiang Chen,
Zhiqiang Gong,
Jin Yang,
Guizhao Shu,
Qi Ning

x

Published: March 6, 2026
https://doi.org/10.1371/journal.pone.0337557

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Bacterial biofilms
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Gallium
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Nitrates
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Escherichia coli
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Bacteria
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Confocal laser microscopy
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Pyruvate
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Scanning electron microscopy
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