Butyrate ameliorates DSS-induced ulcerative colitis in mice by facilitating autophagy in intestinal epithelial cells and modulating the gut microbiota through blocking the PI3K-AKT-mTOR pathway

• Ruifang Li ,

  Contributed equally to this work with: Ruifang Li, Yan Sun

  Roles Conceptualization, Data curation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Center for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, P.R China

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• Yan Sun ,

  Contributed equally to this work with: Ruifang Li, Yan Sun

  Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

  Affiliation Center for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, P.R China

  ⨯
• Drolma Kelsang,

  Roles Methodology, Validation, Visualization

  Affiliation Center for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, P.R China

  ⨯
• Mingzhi Feng,

  Roles Conceptualization, Methodology, Validation

  Affiliation Center for General Practice Medicine, Department of Gastroenterology, Zhejiang Provincial People’s Hospital, (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, P.R China

  ⨯
• Hanhui Cai,

  Roles Methodology, Resources

  Affiliation Emergency and Critical Care Center, Intensive Care Unit, Zhejiang Provincial People’s Hospital, (Affiliated People’s Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, P.R China

  ⨯
• Jun Zhang

  Roles Conceptualization, Methodology, Resources, Writing – review & editing

  * E-mail: zhangjun1@hmc.edu.cn

  Affiliation Department of Gastroenterology, The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou, Zhejiang, P.R China

  https://orcid.org/0000-0003-3618-1723

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