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Open Access
Peer-reviewed
Research Article
Dysbiosis of gut microbiota in C57BL/6-Lepem1hwl/Korl mice during microplastics-caused hepatic metabolism disruption
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Yu Sang Choi ,
Contributed equally to this work with: Yu Sang Choi, Yu Jeong Roh
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Yu Jeong Roh ,
Contributed equally to this work with: Yu Sang Choi, Yu Jeong Roh
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Ji Eun Kim,
Roles Formal analysis, Software
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Hee Jin Song,
Roles Formal analysis, Software
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Ayun Seol,
Roles Formal analysis, Software
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Su Jeong Lim,
Roles Validation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Su Ha Wang,
Roles Validation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Ji Eun Sung,
Roles Validation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Ye Eun Ryu,
Roles Data curation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Ye Ryeong Kim,
Roles Data curation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Hyun Su Park,
Roles Data curation
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Hong Joo Son,
Roles Resources
Affiliation Department of Life Science & Environmental Biochemistry/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Yu Jin Kim,
Roles Resources
Affiliation Department of Life Science & Environmental Biochemistry/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Eun Sang Jung,
Roles Writing – review & editing
Affiliation Department of Bioenvironmental Energy/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Sunho Park,
Roles Writing – review & editing
Affiliation Department of Bio-Industrial Machinery Engineering/Life and Industry Convergence Research Institute, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Dae Youn Hwang
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft
* E-mail: dyhwang@pusan.ac.kr
Affiliation Department of Biomaterials Science (BK21 FOUR Program)/Life and Industry Convergence Research Institute/Laboratory Animal Resources Center, College of Natural Resources & Life Science, Pusan National University, Miryang, Korea
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Dysbiosis of gut microbiota in C57BL/6-Lepem1hwl/Korl mice during microplastics-caused hepatic metabolism disruption
- Yu Sang Choi,
- Yu Jeong Roh,
- Ji Eun Kim,
- Hee Jin Song,
- Ayun Seol,
- Su Jeong Lim,
- Su Ha Wang,
- Ji Eun Sung,
- Ye Eun Ryu,
- Ye Ryeong Kim
- Published: November 20, 2025
- https://doi.org/10.1371/journal.pone.0336627