Low level of plasma DNase is associated with worse clinical outcome in testicular germ cell tumor patients and exogeneous DNase I improves cisplatin treatment efficacy

• Michal Mego ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: misomego@gmail.com

  Affiliations 2nd Oncology Clinic, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia, Translational Research Unit, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  https://orcid.org/0000-0002-6511-6827

  ⨯
• Barbora Vlkova,

  Roles Data curation, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia

  ⨯
• Katarina Kalavska,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Translational Research Unit, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  https://orcid.org/0000-0003-2897-1477

  ⨯
• Michal Pastorek,

  Roles Investigation, Methodology, Visualization, Writing – review & editing

  Affiliation Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia

  ⨯
• Zuzana Cierna,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Pathology, Faculty of Medicine, Comenius University, Bratislava, Slovakia, Department of Pathology, Faculty Hospital, Trnava, Slovakia, Faculty of Health Care and Social Work, Trnava University in Trnava, Trnava, Slovakia

  ⨯
• Zuzana Sestakova,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  ⨯
• Miroslav Chovanec,

  Roles Investigation, Resources, Writing – review & editing

  Affiliation Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  ⨯
• Natalia Udvorkova,

  Roles Investigation, Writing – review & editing

  Affiliation Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  ⨯
• Lucia Kucerova ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors shared last authorship on this work.

  Affiliations Translational Research Unit, Faculty of Medicine, Comenius University and National Cancer Institute, Bratislava, Slovakia, Cancer Research Institute, Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia

  ⨯
• Peter Celec

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ These authors shared last authorship on this work.

  Affiliations Institute of Molecular Biomedicine, Faculty of Medicine, Comenius University, Bratislava, Slovakia, Institute of Pathophysiology, Faculty of Medicine, Comenius University, Bratislava, Slovakia

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