Reconstruction of a genome-scale metabolic model for Streptococcus zooepidemicus: Comparison with Corynebacterium glutamicum to study hyaluronic acid production

Zahra Nikuiyan; Fatemeh Tabandeh; Ehsan Motamedian; Saeed Salehi; Marjan Talebi; Rouzbeh Almasi Ghale

doi:10.1371/journal.pone.0335509

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Open Access

Peer-reviewed

Research Article

Reconstruction of a genome-scale metabolic model for Streptococcus zooepidemicus: Comparison with Corynebacterium glutamicum to study hyaluronic acid production

Zahra Nikuiyan,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

Affiliation Department of Energy and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
⨯
Fatemeh Tabandeh ,

Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: taban_f@nigeb.ac.ir (FT); motamedian@modares.ac.ir (EM)

Affiliation Department of Energy and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

https://orcid.org/0000-0002-4989-7598

⨯
Ehsan Motamedian ,

Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Validation, Writing – review & editing

* E-mail: taban_f@nigeb.ac.ir (FT); motamedian@modares.ac.ir (EM)

Affiliation Department of Biotechnology, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran
⨯
Saeed Salehi,

Roles Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

Current Address: R&D Department, Maya Zist Farayand Co., Tehran, Iran

Affiliation Department of Biotechnology, Faculty of Chemical Engineering, Tarbiat Modares University, Tehran, Iran
⨯
Marjan Talebi,

Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

Affiliations Department of Pharmacognosy, TeMS.C., Islamic Azad University, Tehran, Iran, Herbal Pharmacology Research Center, TeMS.C., Islamic Azad University, Tehran, Iran
⨯
Rouzbeh Almasi Ghale

Roles Formal analysis, Investigation, Methodology, Software, Writing – review & editing

Affiliation Department of Energy and Environmental Biotechnology, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran
⨯

Reconstruction of a genome-scale metabolic model for Streptococcus zooepidemicus: Comparison with Corynebacterium glutamicum to study hyaluronic acid production

Zahra Nikuiyan,
Fatemeh Tabandeh,
Ehsan Motamedian,
Saeed Salehi,
Marjan Talebi,
Rouzbeh Almasi Ghale

Published: December 31, 2025
https://doi.org/10.1371/journal.pone.0335509

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